"Hydroxychloroquine blocks SARS-CoV-2 entry into the endocytic pathway in mammalian cell culture"; this study needs clinical research but in a crisis, with 'precautionary principle', we use it
If a drug has been shown to be prior safe & effective, is available, not harmful, regardless if used for other purposes, with reports of benefit & you have & had nothing available, then you use it
Yet we had many well conducted observational studies that showed strong benefit, so why did the FDA move to block this drug? Was this all to do with Trump? If he said it was no good would we have had HCQ on deck across this pandemic, available? It could have saved tens of thousands of lives.
If there was no alternatives, nothing, it was safe and effective all along, and clinical reports were showing it was highly effective, then why was this drug blocked? Why were the proper studies not done and still, in a crisis, in an emergency, we can mount those studies while we use a therapeutic, empirically, in an emergency, precautionary principle; when there is a threat of harm and nothing is available, you use what suggests works and can work and also is not harmful and not prohibitively expensive etc.; turns out it was blocked and still the NIH and CDC have never, to this date, studied the role of HCQ in COVID…and most studies done were corrupted and designed to fail. Wrong patient group, dose, timing of administration etc. Just pure corruption.
Im a licensed md in NY, NJ and Fl. I am an ophthalmologist . I have many patients who take hydroxychloroquine 200-400 mg PO q day to treat lupus and other auto immune conditions. The FDA does not and has not ever prohibited the the off label use of a drug that FDA has found to be safe as long as there is some evidence it could work and there is proper informed consent. The same with ivermectin.
In putting out “warnings” against these drugs , the fda acted hypocritically and completely abused its power and role . Thousands of people could have been saved by the timely administration of these drugs. The fda was acting under orders from some higher up political authority which was itself taking orders from vax makers (i dont know). There was never any reason to shut down debate on the possible use of IVM or HCQ. They could have sponsored open discussions with experts around the world. We know that HCQ can mitigate lung inflammation. There must be an accounting for why fda did this?
It was blocked because if there are existing treatments you can’t get EUA.