OMINOUS 2016 paper (in PNAS) by Menachery & Baric (Chapel Hill North Carolina) titled "SARS-like WIV1-CoV poised for human emergence"; the results indicate that the WIV1-coronavirus (CoV) cluster has
the ability to directly infect and may undergo limited transmission in human populations. available SARS monoclonal antibodies offered success in limiting viral infection
This 2016 PNAS paper by Menachery and Baric adds to the NATURE publication in 2015. They were actually documenting for us the madness they were doing with gain-of-function (GoF) chimeric research and that they actually were and did create pandemic coronaviruses.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801244/pdf/pnas.201517719.pdf
The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome (MERS)-CoV highlights the continued risk of cross-species transmission leading to epidemic disease. This manuscript describes efforts to extend surveillance beyond sequence analysis, constructing chimeric and full-length zoonotic coronaviruses to evaluate emergence potential. Focusing on SARS-like virus sequences isolated from Chinese horseshoe bats, the results indicate a significant threat posed by WIV1-CoV. Both full-length and chimeric WIV1-CoV readily replicated efficiently in human airway cultures and in vivo, suggesting capability of direct transmission to humans. In addition, while monoclonal antibody treatments prove effective, the SARS-based vaccine approach failed to confer protection. Together, the study indicates an ongoing threat posed by WIV1-related viruses and the need for continued study and surveillance.
Baric must have known it would evolve to a more lethal form under the pressure of mass vaccination, which it has done. When first released it was a mild respiratory pathogen for most and had a low IFR for most people aged less than 80. Getting infected led to asymptomatic or mild illness for most and conferred natural immunity against reinfection. As a result of mass vaccination immune escape variants and subvariants of SARS-CoV-2 have evolved which can reinfect people repeatedly, causing, in the months and years after the acute infection, HIV/AIDS like effects, cancers, diabetes, heart disease, osteoarthritis, gall bladder disease, skin infections, dementia etc and these effects all appear to be made worse by mRNA vaccination.
Isn’t Baric the traitor who worked with female Chinese traitor in Chapel Hill, the North Carolina University to develope Covid? When it came to gain of function they moved and finished Covid in Wuhan and this was paid for and authorized by Fauci! I seem to remember that was what happend when China first stated that Covid came from USA, they weren’t entirely wrong!