Persistence of SARS CoV-2 S1 Protein in CD16+ Monocytes in Post-Acute Sequelae of COVID-19 (PASC) Up to 15 Months Post-Infection
What does this mean? I argue if S 1 sub unit spike is found 15 months post infection, then it is likely also found post vaccine and can explain the long COVID...huge implications
ABSTRACT
The recent COVID-19 pandemic is a treatment challenge in the acute infection stage but the recognition of chronic COVID-19 symptoms termed post-acute sequelae SARS-CoV-2 infection (PASC) may affect up to 30% of all infected individuals. The underlying mechanism and source of this distinct immunologic condition three months or more after initial infection remains elusive. Here, we investigated the presence of SARS-CoV-2 S1 protein in 46 individuals. We analyzed T-cell, B-cell, and monocytic subsets in both severe COVID-19 patients and in patients with post-acute sequelae of COVID-19 (PASC). The levels of both intermediate (CD14+, CD16+) and non-classical monocyte (CD14Lo, CD16+) were significantly elevated in PASC patients up to 15 months post-acute infection compared to healthy controls (P=0.002 and P=0.01, respectively). A statistically significant number of non-classical monocytes contained SARS-CoV-2 S1 protein in both severe (P=0.004) and PASC patients (P=0.02) out to 15 months post-infection. Non-classical monocytes were sorted from PASC patients using flow cytometric sorting and the SARS-CoV-2 S1 protein was confirmed by mass spectrometry. Cells from 4 out of 11 severe COVID-19 patients and 1 out of 26 also contained SARS-CoV-2 RNA. Non-classical monocytes are capable of causing inflammation throughout the body in response to fractalkine/CX3CL1 and RANTES/CCR5.
Thanks Paul for your consistent research and energy to shine a light on the travesty that is this whole situation. I cant help thinking that all this additional research/science should rightfully have been done by the experimental gene therapy developers themselves! Having said that, only the aged & those with known morbidities ever needed to consider this stuff anyway...
Thank you, you are doing real science here. I only hope it doesn't get taken down by the power of BigTech and BigPharma. I dont' mean to hijack your thread, but I am concerned about this so posted an article on my substack asking for help to form a collaborative project of IT professionals who care about freedom and can help build on alternative technologies (AltTech) not dependent on BigTech and outside of BigTech's power to censor. This very platform here on substack is subject to rapid cancellation being that it runs on Jeff Bezo's Amazon Web Services platform. AWS has already begun taking steps against other sites that don't align with leftist censorship thinking. We need contingency plans to keep getting the message out. https://boblphd.substack.com/p/mitigating-internet-risks-from-big/comments