Spike protein may initiate (via COVID gene therapy injection or infection) a catastrophic immune cascade within the Central Nervous System (CNS); Mishra et al.: "SARS-CoV-2 Spike Targets USP33-IRF9...
USP33-IRF9 Axis via Exosomal miR-148a to Activate Human Microglia"; Spike, is able to modify the host exosomal cargo, which gets transported to distant uninfected tissues and organs
We again extrapolate the destruction caused by the spike protein whether via natural infection or via COVID gene injection vaccine.
SOURCE:
https://www.frontiersin.org/articles/10.3389/fimmu.2021.656700/full
‘SARS-CoV-2, the novel coronavirus infection has consistently shown an association with neurological anomalies in patients, in addition to its usual respiratory distress syndrome. Multi-organ dysfunctions including neurological sequelae during COVID-19 persist even after declining viral load. We propose that SARS-CoV-2 gene product, Spike, is able to modify the host exosomal cargo, which gets transported to distant uninfected tissues and organs and can initiate a catastrophic immune cascade within Central Nervous System (CNS). SARS-CoV-2 Spike transfected cells release a significant amount of exosomes loaded with microRNAs such as miR-148a and miR-590. microRNAs gets internalized by human microglia and suppress target gene expression of USP33 (Ubiquitin Specific peptidase 33) and downstream IRF9 levels. Cellular levels of USP33 regulate the turnover time of IRF9 via deubiquitylation. Our results also demonstrate that absorption of modified exosomes effectively regulate the major pro-inflammatory gene expression profile of TNFα, NF-κB and IFN-β. These results uncover a bystander pathway of SARS-CoV-2 mediated CNS damage through hyperactivation of human microglia. Our results also attempt to explain the extra-pulmonary dysfunctions observed in COVID-19 cases when active replication of virus is not supported. Since Spike gene and mRNAs have been extensively picked up for vaccine development; the knowledge of host immune response against spike gene and protein holds a great significance. Our study therefore provides novel and relevant insights regarding the impact of Spike gene on shuttling of host microRNAs via exosomes to trigger the neuroinflammation.’
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Dear Readers,
I also embed this short piece on The Wellness Company and The UNITY Project.
First, The Wellness Company.
I am proud to announce a unique partnership with The Wellness Company and everyone who believes in medical freedom. My dear and esteemed colleagues Dr. Peter McCullough and Dr. Harvey Risch are also in partnership with The Wellness Company which provides telemedicine services for long-haul COVID, vaccine injury, and medical exemptions along with supplements and products that are fully aligned with our values. This support for The Wellness Company stems from the sub-optimal medical care and response that we experienced throughout the pandemic. It became apparent that there are many glaring gaps in our healthcare system and people were not properly treated. Thus, the pivot by us to support The Wellness Company. Take a stand against a broken healthcare delivery system with a membership in The Wellness Company, which directly funds our fight against medical tyranny. Click here The Wellness Company for more information.
I also provide scientific support to The UNITY Project out of California. A magical organization for good. I support this tremendous initiative with some fine colleagues who have been warriors in the fight against all the wrongs in COVID. The UNITY Project aligns with my core values for it is very fierce in its fight to protect children from the danger of the largely safety untested COVID gene injection (The Unity Project Formed by Concerned Parents to Coordinate Opposition to California's K-12 COVID-19 Vaccination Mandate).
Like this: There were no COVID-19 vaccines close to approval on August 27, 2020. In fact, the Pfizer/BioNTech vaccine trial phase 2/3 had only started a month earlier on July 27.
The Initial Contract with General Dynamics
The first contract, with General Dynamics, is dated August 27, 2020. It outlines a series of services the company was to provide to the CDC pursuant to the “anticipated increase” in VAERS reports due to the COVID-19 vaccines.
There is no clause in the contract giving the CDC an option to cancel or suspend the contract in the event that vaccines would not be authorized. Also, the contract stipulates that the contractor would have everything up and running within 60 days of the contract, which means by the end of October. But what if the vaccines were never approved? Or what if they were approved much later, say in February, April or June? Was the CDC just going to hand over [redacted] millions of dollars to the contractor for nothing? Or did the CDC know something about the impending approval of COVID-19 vaccines? It certainly appears that by August, 2020, the impending emergency use authorization of at least one COVID-19 vaccine was a foregone conclusion.
BioNTech CEO Ugur Sahin says that his mRNA vaccines rolled out in January this year (2021): Link here: https://www.ibtimes.sg/fact-check-biontech-ceo-ugur-sahin-refuses-take-pfizer-covid-19-vaccine-due-safety-concerns-61652 but by August 27, 2020 – The first contract, with General Dynamics, is dated August 27, 2020 had been let and the contract states that they were expecting up to 1,000 VAERS reports to be filed per day, with up to 40% of the reports being serious in nature and the CDC was already anticipating that the COVID vaccines might generate nearly seven times as many reports as all other vaccines combined (a 600% increase), with a rate of serious adverse events that could be up to 8 times higher, (bearing in mind that VAERS represents only 1% of all injuries and deaths recorded and multiplying the numbers given by 41 (x41) gives a much better appreciation of just how many American’s were being injured or had died, after vaccinations began in early 2021), on a daily basis: see below
CDC Expected Huge Increase in VAERS Reporting
The contract states that they were expecting up to 1,000 VAERS reports to be filed per day, with up to 40% of the reports being serious in nature:
According to the contract, VAERS had been receiving an annual average of 53,000 reports in recent years, so in contracting for up to 1,000 reports per day, the CDC was already anticipating that the COVID vaccines might generate nearly seven times as many reports as all other vaccines combined (a 600% increase), with a rate of serious adverse events that could be up to 8 times higher.
The initial total amount specified (with options) under the contract with Eagle Health Analytics was $5,925,388.58 or $7,077,054.90 “with all options” (which presumably includes the extension of the VAERS work through July). This amount also includes the CISA project assistance. However, it does not include the increased hours in the Oct. 29 revision, nor the increase for the V-SAFE pregnancy registry work. However, I have not been able to find the contract in any Federal contracts database. Perhaps one of my readers will have better luck.
How Much Did All of This Cost?
The amounts paid out under the contracts with General Dynamics were redacted. But according to this site, the initial amount paid was $9.45 million, with $4.4 million added in late February, and then an additional $16.3 million tacked on in early March. In March of 2022 there was an additional $5.2 million added, though it’s not clear for what since the contract had presumably expired by then. (Best guess is that General Dynamics continued some or all of its work on COVID VAERS reports with Eagle Health brought in for additional support.) Grand total? $35,425,642 of your taxpayer dollars.
So the next time somebody says that VAERS data is worthless, ask them why the Federal government paid contractors at least $45 million dollars over 2 years to maintain this “nationally critical function.”
The Contracts
23 00099 General Dynamics Information Te...
https://substack.com/redirect/dac78dc8-9d2d-4280-a390-218d47bb331d?j=eyJ1IjoibjFlaXcifQ.OkComRnvTz45cW2ospKdwvhGbhkMepFwvepUF91fYF0
23 00099 Eagle Health Analytics, Ll
https://substack.com/redirect/bcba05ff-1dce-4b15-a6a7-0f59f3cb115a?j=eyJ1IjoibjFlaXcifQ.OkComRnvTz45cW2ospKdwvhGbhkMepFwvepUF91fYF0
An anonymous source has sent me (Josh Guetzkow) two key contracts obtained via FOIA between the CDC and two contractors hired to assist with COVID-19 vaccine safety monitoring, including reports to the Vaccine Adverse Events Reporting System (VAERS). “Assist” is not quite the right word, since the contracts essentially outsource VAERS maintenance and reporting for COVID-19 vaccines to these companies. Both contracts are embedded above, of this post.
The above information posted by Josh Guetzkow – which I happened to come across.
Question: There were no COVID-19 vaccines close to approval on August 27, 2020. In fact, the Pfizer/BioNTech vaccine trial phase 2/3 had only started a month earlier on July 27, but It certainly appears that by August, 2020, the impending emergency use authorization of at least one COVID-19 vaccine was a foregone conclusion - from January 2021
.
So the CDC knew that Covid-19 vaccines would cause approximately 1,000 injuries or deaths per day (x41), once they were released for public use – yet the mRNA vaccines went ahead anyway, care of Trump first and Biden later and no mention has been made of the 99% Graphene Oxide and nanotechnology in the Lipid packages, which were injected in their billions in each mRNA vaccine shot – so what do you think of the above – when you “volunteered” to be mRNA vaccinated, but now?
My take on this: But according to this site, the initial amount paid was $9.45 million, (with $4.4 million added in late February, and then an additional $16.3 million tacked on in early March. In March of 2022 there was an additional $5.2 million was added) is that as the numbers went up of records to be processed, so did the amount being paid for that recording to be done - what do you think?
The Vaccine Adverse Event Reporting System (VAERS) Friday updated its numbers showing a staggering 1,481,226 reports of adverse events (x41) following COVID-19 vaccines were submitted between Dec. 14, 2020, and Dec. 9, 2022. ...
All countries around the world have experienced similar trends to what America was recording, so it was hardly surprising that the deaths and injuries due to the synthetic mRNA vaccines would continue to go up, irrespective of which country they were being injected - the facts don't lie, how can they, only the people who said they were safe lied and now their lies have been caught out, agreed?
So this happens to everyone who contracts Covid, whether vaxxed or not? If so, what can be done to prevent it? And this is surely proof of it being a bio-weapon, impacting people whether they are vaxxed or not.