Yahi et al.: "Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccination?; key study...

Potent statement in findings: Thus, ADE may be a concern for people receiving vaccines based on the original Wuhan strain spike sequence (either mRNA or viral vectors).

“Thus, ADE may be a concern for people receiving vaccines based on the original Wuhan strain spike sequence (either mRNA or viral vectors). Under these circumstances, second generation vaccines with spike protein formulations lacking structurally-conserved ADE-related epitopes should be considered.”

What they are saying is if the vaccine is based on the original legacy strain, which it is, then it will fail. So this vaccine is based on the Wuhan strain that is long gone. Makes you ask, why? Why would they bring a failed vaccine that CANNOT work? We are up to Omicron variant and thus there will be immune escape and the mismatch of virus to Abs is catastrophic. This makes even more of a problem given the non-neutralization aspect. The result is sub-optimal immune pressure that will drive infectious variants and a possible lethal one…they even say what is needed are new updated vaccines that can match the spike/antigen target. The vaccine companies have failed to do this. They are concerned with selling their failed stockpile.

SOURCE:

Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccination?