'class-switch' towards immune tolerance (see my prior stacks below on immune tolerance class switch to IgG4 adds to study); key finding: mRNA repeated boosters PROMOTES cancers
https://pmc.ncbi.nlm.nih.gov/articles/PMC8348506/The Good and Bad of Nrf2: An Update in Cancer and New Perspectives in COVID-19 the nrf2 factor seems to display a univocal function in preventing inflammation and cytokine storm that occur under viral infections, specifically in coronavirus disease 19 (COVID-19) Protandim activates the nrf2 protein
yes, this paper is very interesting an raises serious questions about the role of Nrf2 overstimulation due to the mRNA vaccine and thus a subverted role of Nrf2 (transcription factor, key regulator of the oxidative stress response) as an anti-tumour and anti-viral.
I need help with this information as I’m tired, brain fogged, and can’t see well right now. Lol. Sorry
So we want to decrease nrf2? If so how? Is there foods/supplements for this? I’m weak on this topic.
I’m double vaxxed and have been exposed to variants. I’m suffering with lots of issues still even though I’m doing 95% of everything mentioned in protocols. I’m an older female that was battling inflammation prior to the vaxxes from injuries. The darn vaxxes whacked me hard and now have fibromyalgia, severe POTS, and Vaso-spasms that I can feel in right side of brain/neck and can feel in arteries of upper arm with lower leg/arm numbness. My eyesight was affected and I can’t see well sometimes . I live in Canada and can’t get ivermectin.
Does this study change anything that I am doing? Any input is very much appreciated.
You can get Ivermectin from Ezra Healing in BC. The phone no. is: 1-250-444-3972. I've ordered from there and received prompt shipment. While strike is on
they have an alternate delivery service at $33.00 versus $20.00 at Canada Post.
both, it subverts it no doubt day 1 yet across time, as with the effects of HIV infection, the immune system is being grinded down. the boosters data has been frightening and actual bedside medicine, where the more boosters the more chance of being infected, getting severely ill and of dying. there is zero benefit to boosters and zero benefit to the shots in the first place. anyone who says they worked even initially can give you not data to show that and do not consider the role of health vaccinee effect bias, natural exposure immunity, where you recovered or did fine on your own, the effect of early treatment anti infectives and comorbidities etc. still today, there is no proper research in COVID, all is bull shit sup-optimal published research, the methods are wrong and bad, the journal peer review is crap fraud, the journals are fraud now...COVID destroyed all for it was a slow march, COVID hastened the march to the abyss
Fauci had to know of the implications of the class-switch to IgG 4 and of the DNA plasmids and of myriad other concerns. No wonder Biden is reportedly considering pardoning him. If Biden doesn't pardon him, I hope Trump doesn't pardon him either. I also hope that neither of them pardon Bourla. I'd love to know what Trump, RFK Jr and Susie Wiles discussed over dinner at Mar-a-Lago with Bourla and Eli Lilly CEO Dave Ricks. Is Bourla getting a pardon, or a Presidential Commendation like the one Fauci got? If Fauci and Bourla do get pardoned, can they be prosecuted in the ICC? Although the US has not ratified the ICC, it may have jurisdiction elsewhere in the world where Fauci and Bourla have operated. If Fauci and Bourla are arrested and hauled into the dock in the ICC to face charges of crimes against humanity then will the US invoke The Hague Invasion Act and launch a military operation against The Netherlands to rescue them?
superb: "If Biden doesn't pardon him, I hope Trump doesn't pardon him either. I also hope that neither of them pardon Bourla. I'd love to know what Trump, RFK Jr and Susie Wiles discussed over dinner at Mar-a-Lago with Bourla and Eli Lilly CEO Dave Ricks."
I want proper hearings for all of them and if found they costed lives by their OWS policies and vaccines, that they hang if judges say hanging is the punishment. hang them
No,, one cannot recognize the ICC's standing. Fauci's downfall has come on his own terms.. and that is far worse than what any "court" can do to him. History will record his disastrous downfall and outcome. His so called legacy which is important in science is destroyed by his own hand and ego.
I appreciate how you bring topics back around as headlines in your 'stack. This is still important, still news, still happening. Thanks for (responsibly, scientifically) sounding the alarm again.
Fascinating work. I read the abstracts on those papers and I doubt that Fauci knew about the class switch; but that does not mean he is not ultimately guilty of LYING about the BIG PICTURE w/ regard to Sars Covid 2, the masks, efficacy of the fake vaccine(s) by all the companies.
I say that based on the dates of the papers quoted.. 2023. Not only did I not get the vaccine I understand and agree w/ the class switch of the IGA; makes sense from an immunological point of view (the turbo cancer! Issues? who knows?) I of course also agree w/ no boosters ever and no one should continue to take any boosters. Like one of your readers asked: yes the boosters of an unknown lab created vaccine still unknown to this day.. retrospective clinical studies are being analyzed and put out there (like those) the boosters of the MRNA long term continue to keep a human's immune system in a constant state of inflammation or chaos. I can't think of a term to describe that right now.. but yes.. the answer yes. After I got Covid THREE TIMES (naturally) I asked for immunology report and it came back NORMAL levels of IGG IGA etc within normal range.. .(I have been extensively vaccinated prior to Covid since I worked in many hospitals and also military kid) anyway.. one could not tell I had Covid. So there is a LOT which still needs to be looked via retroactive clinical studies like the ones you cited. Thank you. Really great work on your part. I wish I had more time to examine but my vision (the torn retinas and cataract surgeries limit my ability to spend time online. (which is why I have the vision issues to begin w/ working in oncology and science literature online for decades. take care thanks for letting me comment. Have a good weekend. :)
huge hugs, you are welcome to write here for it helps us as we learn from each other...the immune tolerance from IgG 4 class switch is a huge issue...the problem as the IgG4 class switch is linked to cancer.
IgG4 antibodies can bind to anti-tumor IgG1 antibodies and block their interaction with receptors located on effector cells, thus preventing the destruction of cancer cells
class switch due to more boosters. hence seems now we have evidence of more boosters, increased risk of cancer
https://pmc.ncbi.nlm.nih.gov/articles/PMC8348506/The Good and Bad of Nrf2: An Update in Cancer and New Perspectives in COVID-19 the nrf2 factor seems to display a univocal function in preventing inflammation and cytokine storm that occur under viral infections, specifically in coronavirus disease 19 (COVID-19) Protandim activates the nrf2 protein
thank you for sharing this
https://pmc.ncbi.nlm.nih.gov/articles/PMC8348506/
What a very important paper. Thanks for sharing it David.
yes, this paper is very interesting an raises serious questions about the role of Nrf2 overstimulation due to the mRNA vaccine and thus a subverted role of Nrf2 (transcription factor, key regulator of the oxidative stress response) as an anti-tumour and anti-viral.
Thanks for all your articles.
I just made a comment above yours. Do you have any ideas how or what I’m missing? Does this study change anything I’m doing?
Thanks.
I need help with this information as I’m tired, brain fogged, and can’t see well right now. Lol. Sorry
So we want to decrease nrf2? If so how? Is there foods/supplements for this? I’m weak on this topic.
I’m double vaxxed and have been exposed to variants. I’m suffering with lots of issues still even though I’m doing 95% of everything mentioned in protocols. I’m an older female that was battling inflammation prior to the vaxxes from injuries. The darn vaxxes whacked me hard and now have fibromyalgia, severe POTS, and Vaso-spasms that I can feel in right side of brain/neck and can feel in arteries of upper arm with lower leg/arm numbness. My eyesight was affected and I can’t see well sometimes . I live in Canada and can’t get ivermectin.
Does this study change anything that I am doing? Any input is very much appreciated.
You can get Ivermectin from Ezra Healing in BC. The phone no. is: 1-250-444-3972. I've ordered from there and received prompt shipment. While strike is on
they have an alternate delivery service at $33.00 versus $20.00 at Canada Post.
Is it fair to say that the shots and boosters actually impair the immune system, or destroy it?
both, it subverts it no doubt day 1 yet across time, as with the effects of HIV infection, the immune system is being grinded down. the boosters data has been frightening and actual bedside medicine, where the more boosters the more chance of being infected, getting severely ill and of dying. there is zero benefit to boosters and zero benefit to the shots in the first place. anyone who says they worked even initially can give you not data to show that and do not consider the role of health vaccinee effect bias, natural exposure immunity, where you recovered or did fine on your own, the effect of early treatment anti infectives and comorbidities etc. still today, there is no proper research in COVID, all is bull shit sup-optimal published research, the methods are wrong and bad, the journal peer review is crap fraud, the journals are fraud now...COVID destroyed all for it was a slow march, COVID hastened the march to the abyss
Thank you Paul for this summary.
Yes
Fauci had to know of the implications of the class-switch to IgG 4 and of the DNA plasmids and of myriad other concerns. No wonder Biden is reportedly considering pardoning him. If Biden doesn't pardon him, I hope Trump doesn't pardon him either. I also hope that neither of them pardon Bourla. I'd love to know what Trump, RFK Jr and Susie Wiles discussed over dinner at Mar-a-Lago with Bourla and Eli Lilly CEO Dave Ricks. Is Bourla getting a pardon, or a Presidential Commendation like the one Fauci got? If Fauci and Bourla do get pardoned, can they be prosecuted in the ICC? Although the US has not ratified the ICC, it may have jurisdiction elsewhere in the world where Fauci and Bourla have operated. If Fauci and Bourla are arrested and hauled into the dock in the ICC to face charges of crimes against humanity then will the US invoke The Hague Invasion Act and launch a military operation against The Netherlands to rescue them?
yes not just he, all of them linked to mRNA.
superb: "If Biden doesn't pardon him, I hope Trump doesn't pardon him either. I also hope that neither of them pardon Bourla. I'd love to know what Trump, RFK Jr and Susie Wiles discussed over dinner at Mar-a-Lago with Bourla and Eli Lilly CEO Dave Ricks."
I would want to know what a criminal like Bourla is doing there...recall, he called me and others criminals...he did.
I want proper hearings for all of them and if found they costed lives by their OWS policies and vaccines, that they hang if judges say hanging is the punishment. hang them
No,, one cannot recognize the ICC's standing. Fauci's downfall has come on his own terms.. and that is far worse than what any "court" can do to him. History will record his disastrous downfall and outcome. His so called legacy which is important in science is destroyed by his own hand and ego.
I wonder where he is now. Perhaps he is sunning himself on some tropical beach, drinking pina coladas, laughing.
I appreciate how you bring topics back around as headlines in your 'stack. This is still important, still news, still happening. Thanks for (responsibly, scientifically) sounding the alarm again.
Fascinating work. I read the abstracts on those papers and I doubt that Fauci knew about the class switch; but that does not mean he is not ultimately guilty of LYING about the BIG PICTURE w/ regard to Sars Covid 2, the masks, efficacy of the fake vaccine(s) by all the companies.
I say that based on the dates of the papers quoted.. 2023. Not only did I not get the vaccine I understand and agree w/ the class switch of the IGA; makes sense from an immunological point of view (the turbo cancer! Issues? who knows?) I of course also agree w/ no boosters ever and no one should continue to take any boosters. Like one of your readers asked: yes the boosters of an unknown lab created vaccine still unknown to this day.. retrospective clinical studies are being analyzed and put out there (like those) the boosters of the MRNA long term continue to keep a human's immune system in a constant state of inflammation or chaos. I can't think of a term to describe that right now.. but yes.. the answer yes. After I got Covid THREE TIMES (naturally) I asked for immunology report and it came back NORMAL levels of IGG IGA etc within normal range.. .(I have been extensively vaccinated prior to Covid since I worked in many hospitals and also military kid) anyway.. one could not tell I had Covid. So there is a LOT which still needs to be looked via retroactive clinical studies like the ones you cited. Thank you. Really great work on your part. I wish I had more time to examine but my vision (the torn retinas and cataract surgeries limit my ability to spend time online. (which is why I have the vision issues to begin w/ working in oncology and science literature online for decades. take care thanks for letting me comment. Have a good weekend. :)
huge hugs, you are welcome to write here for it helps us as we learn from each other...the immune tolerance from IgG 4 class switch is a huge issue...the problem as the IgG4 class switch is linked to cancer.
IgG4 antibodies can bind to anti-tumor IgG1 antibodies and block their interaction with receptors located on effector cells, thus preventing the destruction of cancer cells
stop spamming me
The only one who "LIKES" laura's comment............. is laura.
B O T
https://substack.com/@laura964653