Jeremy Howick, Ioannidis et al.: "Most healthcare interventions tested are not effective according to high quality evidence: a systematic review and meta-analysis"
In this large sample of 1567 drugs, interventions studied...effects of most interventions (94%) interventions were not supported by high quality evidence.
“Patients, doctors, and policy makers should consider the lack of high-quality evidence supporting the benefits and harms of many interventions in their decision-making.”
SOURCE:
“Of 1567 eligible interventions, 87 (5.6%) had high quality evidence on first-listed primary outcomes, positive, statistically significant results and were rated by review authors as beneficial. Harms were measured for 577 (36.8%) interventions, 127 of which (8.1%) had statistically significant evidence of harm. Our dependence on the reliability of Cochrane author assessments (including their GRADE assessments) was a potential limitation of our study.”
Not surprised by the findings. But trusting Cochrane or any medical " authority" is a real problem for me now also. Such a sad situation for us all. I do know that in US the elderly people put on hospice and removed from most of their prescription drugs end up living longer than people who stay on the drugs until the end.
What a gutsy thing to publish.
John Ioannidis (Stanford) is considered by many as one of the leading epidemiologists and physician-scientists alive today.
It appears they may have empirically demonstrated a preponderance of the modern public health and institutional medicine health care paradigm is literally founded on shit data fatally lacking sufficient quality to support the policy and presumptions of care being actively promoted by these institutions and their employees.
The Collins/Fauci-era, Big Med and public health institutions we see today need a hostile takeover, radical reorganization and right-sizing. These institutional zombies must die... before they harvest the lives and livelihoods of any more innocent people by fiat of pernicious maladministration and an enabling deviant executive culture that has normalized depraved indifference regarding the industrial monetization of individual human suffering.