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S. Vlachos & Pita-Juarez et al.: "A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver (liver damage) reveals topological, functional, and regenerative organ disruption in patients"

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S. Vlachos & Pita-Juarez et al.: "A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver (liver damage) reveals topological, functional, and regenerative organ disruption in patients"

revealed extensive changes in the cellular composition and expression states in COVID-19 liver, reflecting hepatocellular injury, ductular reaction, pathologic vascular expansion, and fibrogenesis.

Dr. Paul Alexander
Oct 30, 2022
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S. Vlachos & Pita-Juarez et al.: "A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver (liver damage) reveals topological, functional, and regenerative organ disruption in patients"

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“Profiling of livers from 17 COVID-19 decedents. We identified hepatocytes positive for SARS-CoV-2 RNA with an expression phenotype resembling infected lung epithelial cells. Integrated analysis and comparisons with healthy controls revealed extensive changes in the cellular composition and expression states in COVID-19 liver, reflecting hepatocellular injury, ductular reaction, pathologic vascular expansion, and fibrogenesis. We also observed Kupffer cell proliferation and erythrocyte progenitors for the first time in a human liver single-cell atlas, resembling similar responses in liver injury in mice and in sepsis, respectively.”

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A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients

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S. Vlachos & Pita-Juarez et al.: "A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver (liver damage) reveals topological, functional, and regenerative organ disruption in patients"

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S. Vlachos & Pita-Juarez et al.: "A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver (liver damage) reveals topological, functional, and regenerative organ disruption in patients"

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Janet Morrison
Oct 30, 2022

So, no other virus causes these actual changes in liver or lung cells. Does this lend proof to the fact that the COVID virus is man-made?

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Potatodots
Oct 30, 2022

This is interesting. The authors also point out these cases are from before the injections were available. There were some nasty clusters on the East coast (my memory), and I remember seeing comment that the virus in NY was different enough from patient zero's in King County WA to be remarked upon by those sequencing, etc. I do not doubt that there were seedings of nastier ones, and there was a too coordinated set out "outbreaks" in places. I also believe the virus was going around a year plus (Italy, France) before 2020, but like any virus, became less vigorous in 6-9 months. What with certain comorbidities upping the likelihood of worse outcomes, and Hospitals and ERs, depending on the practitioners and the hospital policies, were under different duresses in treating.

This virus was made to harm people, if not in the near term, in the long term. Common post-infection sequelae for Wuhan versions were suppressed CD4+ and CD8+, iron anemia. fatigue, susceptibility to other respiratory infections.

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