see study by Kurhade et al. challenging utility of mRNA bivalent booster: "Low neutralization of SARS-CoV-2 Omicron BA.2.75.2, BQ.1.1, and XBB.1 by parental mRNA vaccine or a BA.5-bivalent booster"

Dr. Harvey Risch & Dr. Oskoui shared; this adds to existing evidence of the failure of the bivalent booster (original antigenic sin, viral immune escape, antibody-enhancement of infection and disease)

I have adjusted the Annual Membership fee: I have reduced the yearly membership fee to $39.99 per year (for those who chose to subscribe with some support yet it can be free as it has always been with no restrictions to comment etc.), which is $3.30 per month and about $0.83 per week and thus $0.11 per day; I am very very grateful for your loyalty and decided to reduce the annual fee to show my appreciation for your loyalty and support.

Now to the study:

First, in as clear a language as possible, the COVID gene injections vaccines especially mRNA, have failed, fully, miserably. And are dangerous.

The bivalent booster is garbage and junk, failed. Do not touch it!

The researchers concluded,

‘Previous infection significantly enhanced the magnitude and breadth of BA.5-bivalent-booster-elicited neutralization. Our data support a vaccine update strategy that future boosters should match newly emerged circulating SARS-CoV-2 variants.’

Duh? You would think? Of course original antigenic sin would feature (OAS) and it begs the question, why did they develop this bivalent booster knowing full well that there were sub-variants already pressing and emerging that were already supplanting BA.4 and BA.5 e.g. BQ.1.1. It is almost as if they, CDC, NIH, FDA, Pfizer et al. do everything to fail! It is sheer incompetence. BA.2.75.2-, BQ.1.1-, and XBB.1-spike appear largely resistant to the BA.5 bivalent booster vaccinal antibodies.

Bottom line is if the vaccinal antibodies are a mismatch to the prevailing virus antigen (existing dominating epitopes), then there will not be neutralization and there will be selection pressure on the antigen (to drive selection of more infectious and potentially virulent variants). Recalled antibodies are to the initial strain and the bivalent booster cannot work if the prevailing strain is now BQ.1.1 and BQ.1.

Findings:

‘The newly emerged SARS-CoV-2 Omicron sublineages, including the BA.2-derived BA.2.75.2 and the BA.5-derived BQ.1.1 and XBB.1, have accumulated additional spike mutations that may affect vaccine effectiveness.’

‘report neutralizing activities of three human serum panels collected from individuals 23–94 days after dose 4 of a parental mRNA vaccine, 14–32 days after a BA.5-bivalent-booster from individuals with 2–4 previous doses of parental mRNA vaccine, or 15–32 days after a BA.5-bivalent-booster from individuals with previous SARS-CoV-2 infection and 2–4 doses of parental mRNA vaccine.’

The results showed that a BA.5-bivalent-booster elicited a high neutralizing titer against BA.4/5 measured at 14- to 32-day post-boost; however, the BA.5-bivalent-booster did not produce robust neutralization against the newly emerged BA.2.75.2, BQ.1.1, or XBB.1.’

Look at the wild-type response (neutralizing activity) in all three graphs (extreme left vertical lines).

See the updated Variant Proportions as of today as reported by CDC. We see that BQ.1.1 and BQ.1 account for near 70% of the variants and BA.5 has declined to 11%. XBB is at 4.7%.

SOURCE:

https://covid.cdc.gov/covid-data-tracker/#variant-proportions

SOURCE:

https://www.nature.com/articles/s41591-022-02162-x

Order via this LINK

I also embed this short piece on The Wellness Company and The UNITY Project.

First, The Wellness Company.

I am proud to announce a unique partnership with The Wellness Company and everyone who believes in medical freedom. My dear and esteemed colleagues Dr. Peter McCullough and Dr. Harvey Risch are also in partnership with The Wellness Company which provides telemedicine services for long-haul COVID, vaccine injury, and medical exemptions along with supplements and products that are fully aligned with our values. This support for The Wellness Company stems from the sub-optimal medical care and response that we experienced throughout the pandemic. It became apparent that there are many glaring gaps in our healthcare system and people were not properly treated. Thus, the pivot by us to support The Wellness Company. Take a stand against a broken healthcare delivery system with a membership in The Wellness Company, which directly funds our fight against medical tyranny. Click here The Wellness Company for more information. 

I also provide scientific support to The UNITY Project out of California. I support this tremendous initiative with some fine colleagues who have been warriors in the fight against all the wrongs in COVID. The UNITY Project aligns with my core values for it is very fierce in its fight to protect children from the danger of the largely safety untested COVID gene injection (The Unity Project Formed by Concerned Parents to Coordinate Opposition to California's K-12 COVID-19 Vaccination Mandate).

Alexander COVID News-Dr. Paul Elias Alexander's Newsletter is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.