Bob M sad, Bob sad; this is a good stack by SAGE for it underscores fraud & duplicity of Malone & SAGE HANA deserves credit for keeping Malone's nuts, with Weissman, Kariko & her nuts, Bourla, Sahin
Bob M sad, Bob sad; this is a good stack by SAGE for it underscores fraud & duplicity of Malone & SAGE HANA deserves credit for keeping Malone's nuts, with Weissman, Kariko & her nuts, Bourla, Sahin
& Bancel & their mRNA vaccine nuts in the fire for these are the 6 we must focus on first, along with the other among the 43 COVID Apocalypse Horsemen, for courts, judges, tribunals, jails, hangings!
Reading research papers may seem like learning a foreign language but the average person can do it. Understanding the language doesn’t take a genius. If you expect your doctor to read them, then you are a fool. They wait for the pharmaceutical rep to tell them what to do. 🥴
Wow. In addition to the news of this girl's untimely death after a covid shot making Malone "so sad," he posts that it was also "very timely" for HIM since he was at that very moment writing a substack on the very same issue. Only a cold-hearted opportunist could use an expression of sympathy as a cover for blatant self-promotion.
This,below, was published a year ago. Has Malone even acknowledged yet that reverse transcription and genomic integration is possible?
Potential health risks of mRNA-based vaccine therapy: A hypothesis
K. Acevedo-Whitehousea,⁎ and R. Brunob
Med Hypotheses 2023 Feb; 171: 111015.
Published online 2023 Jan 25. doi: 10.1016/j.mehy.2023.111015
Abstract
"Therapeutic applications of synthetic mRNA were proposed more than 30 years ago, and are currently the basis of one of the vaccine platforms used at a massive scale as part of the public health strategy to get COVID-19 under control. To date, there are no published studies on the biodistribution, cellular uptake, endosomal escape, translation rates, functional half-life and inactivation kinetics of synthetic mRNA, rates and duration of vaccine-induced antigen expression in different cell types. Furthermore, despite the assumption that there is no possibility of genomic integration of therapeutic synthetic mRNA, only one recent study has examined interactions between vaccine mRNA and the genome of transfected cells, and reported that an endogenous retrotransposon, LINE-1 is unsilenced following mRNA entry to the cell, leading to reverse transcription of full length vaccine mRNA sequences, and nuclear entry. This finding should be a major safety concern, given the possibility of synthetic mRNA-driven epigenetic and genomic modifications arising. We propose that in susceptible individuals, cytosolic clearance of nucleotide modified synthetic (nms-mRNAs) is impeded. Sustained presence of nms-mRNA in the cytoplasm deregulates and activates endogenous transposable elements (TEs), causing some of the mRNA copies to be reverse transcribed. The cytosolic accumulation of the nms-mRNA and the reverse transcribed cDNA molecules activates RNA and DNA sensory pathways. Their concurrent activation initiates a synchronized innate response against non-self nucleic acids, prompting type-I interferon and pro-inflammatory cytokine production which, if unregulated, leads to autoinflammatory and autoimmune conditions, while activated TEs increase the risk of insertional mutagenesis of the reverse transcribed molecules, which can disrupt coding regions, enhance the risk of mutations in tumour suppressor genes, and lead to sustained DNA damage. Susceptible individuals would then expectedly have an increased risk of DNA damage, chronic autoinflammation, autoimmunity and cancer. In light of the current mass administration of nms-mRNA vaccines, it is essential and urgent to fully understand the intracellular cascades initiated by cellular uptake of synthetic mRNA and the consequences of these molecular events."
If I remember correctly he told Dr Nagase that it was not significant and had not been established in clinical trials, so don't worry about it. Sage Hana did a Substack about it.
This abstract hit me like a runaway train. And a year later...how many of the recommended studies that would have been prudent to do before 'covid vaccine rollout' to the general population have been done?
Good post, Paul. You clarified something for me regarding how the lipid nanoparticle moves. It's still so unclear what's in those shots. It seems like there are 3 different camps on this: 1) mRNA camp, 2) venom peptide camp, and 3) no mRNA but nanotech. Does anyone have any thoughts on this? I'm trying to get clarification to help others understand. Either way, all toxic and need to be detoxed safely from the body immediately.
Can someone explain what malone is talking about when he writes "after getting the psuedo-mRNA vaccine.."? He's still calling it a vaccine?
we will fix Drew, today...I intervoew him to clarify...he cannot be for this vaccine shit in any form. not now, ever...people can evolve, I grant...bull shit they needed time and people were hurt, they will need reconcile with their Gods and it is not me or you...we must be thankful they are waging for the right side now...Drew that I know is a good man...I comment on what I know...I dont hate someone because others may not like them...my relationship is mine...he is saying the right things now...but he has some buttoning up to do...I grant him space...
Reading research papers may seem like learning a foreign language but the average person can do it. Understanding the language doesn’t take a genius. If you expect your doctor to read them, then you are a fool. They wait for the pharmaceutical rep to tell them what to do. 🥴
Wow. In addition to the news of this girl's untimely death after a covid shot making Malone "so sad," he posts that it was also "very timely" for HIM since he was at that very moment writing a substack on the very same issue. Only a cold-hearted opportunist could use an expression of sympathy as a cover for blatant self-promotion.
This,below, was published a year ago. Has Malone even acknowledged yet that reverse transcription and genomic integration is possible?
Potential health risks of mRNA-based vaccine therapy: A hypothesis
K. Acevedo-Whitehousea,⁎ and R. Brunob
Med Hypotheses 2023 Feb; 171: 111015.
Published online 2023 Jan 25. doi: 10.1016/j.mehy.2023.111015
Abstract
"Therapeutic applications of synthetic mRNA were proposed more than 30 years ago, and are currently the basis of one of the vaccine platforms used at a massive scale as part of the public health strategy to get COVID-19 under control. To date, there are no published studies on the biodistribution, cellular uptake, endosomal escape, translation rates, functional half-life and inactivation kinetics of synthetic mRNA, rates and duration of vaccine-induced antigen expression in different cell types. Furthermore, despite the assumption that there is no possibility of genomic integration of therapeutic synthetic mRNA, only one recent study has examined interactions between vaccine mRNA and the genome of transfected cells, and reported that an endogenous retrotransposon, LINE-1 is unsilenced following mRNA entry to the cell, leading to reverse transcription of full length vaccine mRNA sequences, and nuclear entry. This finding should be a major safety concern, given the possibility of synthetic mRNA-driven epigenetic and genomic modifications arising. We propose that in susceptible individuals, cytosolic clearance of nucleotide modified synthetic (nms-mRNAs) is impeded. Sustained presence of nms-mRNA in the cytoplasm deregulates and activates endogenous transposable elements (TEs), causing some of the mRNA copies to be reverse transcribed. The cytosolic accumulation of the nms-mRNA and the reverse transcribed cDNA molecules activates RNA and DNA sensory pathways. Their concurrent activation initiates a synchronized innate response against non-self nucleic acids, prompting type-I interferon and pro-inflammatory cytokine production which, if unregulated, leads to autoinflammatory and autoimmune conditions, while activated TEs increase the risk of insertional mutagenesis of the reverse transcribed molecules, which can disrupt coding regions, enhance the risk of mutations in tumour suppressor genes, and lead to sustained DNA damage. Susceptible individuals would then expectedly have an increased risk of DNA damage, chronic autoinflammation, autoimmunity and cancer. In light of the current mass administration of nms-mRNA vaccines, it is essential and urgent to fully understand the intracellular cascades initiated by cellular uptake of synthetic mRNA and the consequences of these molecular events."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876036/
like it, will share...see this by Alden et al...
https://pubmed.ncbi.nlm.nih.gov/35723296/
hugs, we are at war....prepare...
If I remember correctly he told Dr Nagase that it was not significant and had not been established in clinical trials, so don't worry about it. Sage Hana did a Substack about it.
This abstract hit me like a runaway train. And a year later...how many of the recommended studies that would have been prudent to do before 'covid vaccine rollout' to the general population have been done?
Good post, Paul. You clarified something for me regarding how the lipid nanoparticle moves. It's still so unclear what's in those shots. It seems like there are 3 different camps on this: 1) mRNA camp, 2) venom peptide camp, and 3) no mRNA but nanotech. Does anyone have any thoughts on this? I'm trying to get clarification to help others understand. Either way, all toxic and need to be detoxed safely from the body immediately.
Can someone explain what malone is talking about when he writes "after getting the psuedo-mRNA vaccine.."? He's still calling it a vaccine?
Wish Dr Drew had been so “Sage”.
So sad.
Maloney continues his Balony
we will fix Drew, today...I intervoew him to clarify...he cannot be for this vaccine shit in any form. not now, ever...people can evolve, I grant...bull shit they needed time and people were hurt, they will need reconcile with their Gods and it is not me or you...we must be thankful they are waging for the right side now...Drew that I know is a good man...I comment on what I know...I dont hate someone because others may not like them...my relationship is mine...he is saying the right things now...but he has some buttoning up to do...I grant him space...
❤
Malone doesn’t take you seriously.
That’s on you.
He can’t throw you off a bus
You never got on.